Today I'm talking about the Fermi Paradox in my astro-for-physics-majors class (and I'll talk about it again on Friday in my astro 101 class).
It's a really simple question with completely terrifying/mind-blowing implications, first asked by Enrico Fermi (who, ironically, was one of the Manhattan project scientists...)
Our universe is 13.8 billion years old, our Galaxy is at least 10 billion years old, other planets are surely much older than Earth, with more time to involve intelligent life.